Pharmaceutical Drug Analysis

With the advent of computer-aided-drug modeling (CADM) the critical, scientific and faster approach to newer drug entities based on the biologically active prototypes, combinatorial chemistry, chiral chemistry and biotechnology has paved the way towards more specific, potent and above all less toxic ‘drugs’ to improve the ultimate quality of life in humans. Keeping in view the above astronomical growth in the design of complicated, specific and highly active drug molecules an equally viable, rigorous, accurate and precise analytical methods have been evolved with the passage of time which have now occupied pivotal and vital positions in most of the Official Compendia viz., USP, BP, Int.P., Eur. P, IP etc., for the analysis of such compounds both in pure and dosage forms.
The articulated developments in the fields of science and technology being utilized as on date, amalgamated with relatively stringent new regulations, namely: Federal Drug Authority (FDA); International Conference on Harmonization (ICH); Current Good Manufacturing Practices (cGMP); Pre-Approval Inspections (PAIs) and the like are now serving as a ‘legal binding’ specifically for the pharmaceutical drug analysis even much more complicated in comparison to the situation prevailing almost two decades ago.

This revised textbook on ‘Pharmaceutical Drug Analysis’ caters for the much needed handbook and reference book, which is absolutely current with regard to the esteemed philosophy of analytical chemistry, an obvious solid support towards drug discovery, development, stability studies, bioavailability and pharmacokinetic studies, and above all the quality assurance of pure drugs together with their respective dosage forms. The thirty-two different chapters meticulously divided into six parts invariably covers up analytical techniques being used in most of the Official Compendia. Each chapter categorically and explicitly deals with the introduction, theoretical aspect(s), instrumentation, typical examples of pharmaceutical analysis and cognate assays.

I guess this textbook on ‘Pharmaceutical Drug Analysis’ would enormously serve the undergraduates, postgraduates, researchers, analytical chemists working in the Quality Assurance Laboratories, new drug development, production and control, teaching, or regulatory authorities.